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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Ann Neurol. 2008 Nov;64(5):583–587. doi: 10.1002/ana.21522

Table 1.

Transplantation Data

Patient age/Gender at UCBT 8 years/Male 6 years/Male 4 years/Female
UCB-HLA match 5/6 Mismatch at B 4/6 Mismatch at A&B 4/6 Mismatch at A&B
CD34+/kg 5.1 x 105/kg 6.0 x 105/kg 1.5 x 106/kg
Conditioning regimen IV Busulfan with pharmacokinetics, Cyclophosphamide, alemtuzumab IV Busulfan with pharmacokinetics, Cyclophosphamide, thymoglobulin IV Busulfan with pharmacokinetics, Cyclophosphamide, thymoglobulin
GVHD prophylaxis Tacrolimus, methylprednisolone Tacrolimus, methylprednisolone Tacrolimus, methylprednisolone
Time until engraftment Neutrophil=N Platelet=P N:Day +24 P:Day +30 N:Day +18 P:Day +43 N:Day +5 P:Day +41
GVHD (overall) Grade III (skin, gut) None None
Complications CMV colitis Chronic sinusitis BK viral infection Hemorrhagic cystitis Right ankle infection Chronic sinusitis Hypothyroidism