TABLE 2.
Characteristics of 181 Patients Age ≥ 16 Who Died from Low Grade Sarcoma Following Resection with Curative Intent
Characteristic | Number (N=182) |
% | |
---|---|---|---|
Gender | Male | 98 | 54 |
Female | 83 | 46 | |
Age at Diagnosis | Median 57 (16 – 90) |
||
Site | Extremity | 32 | 18 |
Retroperitoneal/Intraabdominal | 97 | 54 | |
Trunk | 19 | 10 | |
Thoracic | 8 | 4 | |
Visceral¶ | 14 | 8 | |
Head and Neck | 10 | 6 | |
Skin | 1 | 0.5 | |
Histology | Liposarcoma | 97 | 53 |
Desmoid/Fibromatosis† | 7 | 4 | |
Dermatofibrosarcoma Protuberans (DFSP) | 1 | 0.5 | |
Malignant Fibrous Histiocytoma | 21 | 12 | |
Leiomyosarcoma | 12 | 7 | |
Solitary Fibrous Tumor/Hemangiopericytoma | 6 | 3 | |
Fibrosarcoma | 14 | 8 | |
Chondrosarcoma¶¶ | 7 | 4 | |
Other†† | 16 | 9 | |
Primary Tumor Size | ≤ 5 cm | 10 | 6 |
5-10 cm | 50 | 28 | |
> 10 cm | 105 | 58 | |
Unknown | 16 | 9 | |
Depth | Deep | 169 | 93 |
Superficial | 11 | 6 | |
Margin Status | R0 | 82 | 45 |
R1 | 56 | 31 | |
R2 | 29 | 16 | |
Unknown | 14 | 8 | |
Radiotherapy | Primary Tumor | 42 | 23 |
Recurrent Disease | 52 | 29 | |
Chemotherapy | Primary Tumor | 22 | 12 |
Recurrent Disease | 82 | 45 | |
Cause of Death | Local | 105 | 58 |
Distant | 59 | 32 | |
Unknown | 17 | 9 | |
Median Time to Recurrence |
Local | 29 months (range 1 – 382) |
|
Distant | 74 months (range 1 – 414) |
||
Median Time to Sarcoma-Specific Death |
Local | 94 months (range 3 – 328) |
|
Distant | 168 months (range 9 – 432) |
Because of rounding, not all percentages sum to 100.
Includes gynecologic 6/14 (43%), gastrointestinal 7/14 (50%), and genitourinary 1/14 (7%).
Analyses performed excluding patients with desmoids/fibromatosis obtained similar results.
Includes extraskeletal myxoid chondrosarcoma 7/7 (100%)
Comprises 9 histologic subtypes including endometrial stromal sarcoma, adenosarcoma, angiosarcoma, dendritic cell tumor, malignant mesenchymoma, and sarcoma NOS among others.