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. 2008 Dec 22;205(13):2975–2984. doi: 10.1084/jem.20081800

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© 2008 Orešič et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 6. — Biochemical model of metabolic changes in progressors to type 1 diabetes prior and after seroconversion to islet autoimmunity. Detected changes of specific metabolites of citric acid cycle and glutamic acid metabolism before (left boxes) and shortly after (right boxes) the appearance of GADA are shown.