Table I.
Selected characteristics of the subjects included in the study.
| Progressors | Nonprogressors | |
|---|---|---|
| Gender (girls, boys) | 31, 25 | 40, 33 |
| City of birth (Turku, Oulu) | 29, 27 | 45, 28 |
|
Season at time of birtha (winter, spring, summer, autumn) |
11, 19, 14, 12 | 15, 25, 19, 14 |
|
Season at time of diagnosis (winter, spring, summer, autumn) |
11, 21, 10, 13 | NA |
|
Age at time of diagnosis (median, range in months) |
44, 6–162 | NA |
|
Age at time of first seroconversion (median, range in months) |
12, 6–96 | NA |
| HLA risk haplotypes | ||
| Moderate riskb DR4-DQ8/x (x = any haplotype except DR2-DQ6, DR5-DQ7 or DR3-DQ2) |
33 | 46 |
| High risk (DR3-DQ2/DR4-DQ8) | 17 | 20 |
a
Seasons are defined as winter for December to February, spring for March to May, summer for June to August, and autumn for September to November.
b
HLA genotype information is shown for the DIPP children only. One nonprogressor, not included in the table, had the moderate risk DR3-DQ2/x haplotype.