Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Dec 22;205(13):2959–2964. doi: 10.1084/jem.20081611

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2008 Iguchi-Manaka et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 3. — DNAM-1 is involved in immune surveillance against MCA-induced fibrosarcoma. (A) WT (n = 10) or DNAM-1–deficient (n = 10) mice were injected s.c. with 400 μg or 25 μg MCA on day 0. Tumor size in each mouse was measured once a week. Tumor incidence and survival data for 10 mice per group are shown. (B) When 25 μg MCA-induced fibrosarcomas in seven WT or nine DNAM-1–deficient mice reached a size of 1 cm in diameter, fibrosarcoma was resected from each mouse and subjected to quantitative RT-PCR for CD155 and CD112. The skins resected from four naive mice were also subjected to quantitative RT-PCR. The data are the mean of triplicates. The experiments were performed twice with similar results. One experiment is shown.