Table 1.
DAOA and Risk for Schizophrenia: Haplotype and SNP Results
| Haplotype SNP Allele(s) | Global χ2 (df=2) | Global p-value | Frequency Total | Frequency Cases | Frequency Controls | Pearson χ2 (df=1) | P-value |
|---|---|---|---|---|---|---|---|
| Block 1 | 7.20 | 0.03 | -- | -- | -- | -- | |
| ACGGT | --- | --- | 0.482 | 0.454 | 0.516 | 2.405 | 0.121 |
| GCGGC | --- | --- | 0.168 | 0.201 | 0.127 | 6.179 | 0.013 |
| ATATC | --- | --- | 0.162 | 0.150 | 0.177 | 0.88 | 0.348 |
| rs1570709 G | --- | --- | 0.219 | 0.133 | 8.318 | 0.0039 | |
| Block 2 | 4.49 | 0.11 | --- | --- | --- | --- | --- |
| Block 3 | 0.87 | 0.65 | --- | --- | --- | --- | --- |
| Block 4 | 1.45 | 0.48 | --- | --- | --- | --- | --- |
| Block 5 | 1.07 (df=3) | 0.78 | --- | --- | --- | --- | --- |
| Block 6 | 2.23 | 0.33 | --- | --- | --- | --- | --- |
| Block 7 | 0.21 | 0.90 | --- | --- | --- | --- | --- |
| Block 8 | 3.62 | 0.16 | --- | --- | --- | --- | --- |
Note: Unless indicated otherwise (alleles in bold script), all alleles refer to the (-) strand relative to the human reference sequence, as provided by manufacturer’ s probe list annotations (https://www.affymetrix.com/analysis/netaffx/batch_query.affx?netaffx=mapping). Global p value and χ2 was calculated applying a Fishers Exact Test in VassarStats