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. Author manuscript; available in PMC: 2009 Nov 13.
Published in final edited form as: Cell Host Microbe. 2008 Nov 13;4(5):447–457. doi: 10.1016/j.chom.2008.09.007

Figure 5. Specificity of ECF-σ-linked PULs for O-glycan components.

Figure 5

(A) Representative core 2 mucin O-glycan structure. Two common disaccharides, core 1 and N-acetyllactosamine (LacNAc), are highlighted by orange- and green-shaded boxes, respectively. Monosaccharide symbols: GalNAc (open squares); Gal (closed circles); GlcNAc (closed squares); Fuc (open triangles); and NeuNAc (closed diamonds). (B) GeneChip-based induction values for genes in the BT4631-36 locus during growth on equimolar amounts of core 1 monosaccharides, core 1 disaccharide, LacNAc monosaccharides, and LacNAc disaccharide. Values are expressed as fold-difference relative to growth on MM-glucose. Color codes are the same in B–D. (C) Responses of genes in the BT2559-62 locus to growth on O-glycan mono- and disaccharide components. (D) Responses of genes in the BT4244-50 locus to growth on O-glycan mono- and disaccharide components. Note the differing substrate specificities for LacNAc and core 1 disaccharides. Values represent the mean±range of two biological replicates performed for each substrate.