TABLE 3.
Axotomized + | Slow Only | Fast/Slow Combination | Fast Only | Total |
---|---|---|---|---|
Vehicle perfusion | 0 | 6 | 10 | 16 |
NGF perfusion | 3* | 10* | 6 | 19 |
Values are numbers of neurons. For abbreviations, see Table 2.
NGF (0.25 μg/μl) was deliverd directly to the transected sciatic nerve stump in vivo at 0.5 μl/h for 14 days. Delivery of vehicle solution served as a control.
P < 0.001 with respect to the occurrence of the slow Na+ current in 6 of 16 neurons after vehicle treatment as determined by χ2 formulation with 2 degrees of freedom.