Fig. 4.

Electron micrographs of remyelinated axons in the dorsal funiculus of the spinal cord after bone marrow transplantation. A: Many myelin-forming cells were similar to peripheral myelin-forming cells, characterized by large nuclear and cytoplasmic regions, and collagen (arrows) in the extracellular space. B: Several of the myelin-forming cells have multilobular nuclei in the BM transplantation group. C: Some of the myelin-forming cells in the BM transplantation group engaged more than one axon, while no Schwann cells were observed to engage more than one axon. Arrows in C point to a basement membrane surrounding the myelin-forming cell. Scale bar = 1 μm in A,B; 2 μm in C.