Table 3.
Primary afferent evoked EPSPs in laminae II–III neurons
| Type of EPSPs | n = | Latency (msec) | Peak amplitude (mV) | EPSP slope (dV/dT) | Number of peaks | |
|---|---|---|---|---|---|---|
| Lamina II | ||||||
| Control | Low-threshold mono | 1 | 2.1 | 14.5 | 8.5 | 1.0 |
| Low-threshold poly | 6 | — | 13.7 ± 2.8 | — | 2.8 ± 1.2 | |
| High-threshold mono | 27 | 2.4 ± 1.2 | 11.8 ± 3.7 | 6.3 ± 2.7 | 1.2 ± 0.4 | |
| High-threshold poly | 2 | — | 16.1 ± 2.9 | — | 2.5 ± 0.7 | |
| Axotomy | Low-threshold mono | 13 | 1.9 ± 0.5 | 15.5 ± 4.0** | 11.7 ± 3.6*** | 2.3 ± 1.4* |
| Low-threshold poly | 18 | — | 20.3 ± 6.6 | — | 2.9 ± 1.0 | |
| High-threshold mono | 19 | 2.5 ± 1.1 | 11.9 ± 4.3 | 7.1 ± 2.8 | 1.4 ± 0.5 | |
| High-threshold poly | 2 | — | 17.6 ± 3.9 | — | 2.5 ± 0.7 | |
| Lamina III | ||||||
| Control | Low-threshold mono | 16 | 1.8 ± 0.3 | 17.5 ± 2.6 | 14.0 ± 2.2 | 2.9 ± 1.5 |
| Low-threshold poly | 7 | — | 17.3 ± 2.6 | — | 2.4 ± 0.5 | |
| High-threshold poly | 3 | — | 18.7 ± 2.2 | — | 2.3 ± 0.6 | |
| Axotomy | Low-threshold mono | 15 | 1.7 ± 0.3 | 17.1 ± 1.7 | 12.5 ± 2.6 | 2.6 ± 1.6 |
| Low-threshold poly | 6 | — | 16.4 ± 2.6 | — | 2.8 ± 0.8 | |
| High-threshold poly | 1 | — | 16.2 | — | 2.0 |
Data are presented as mean ± SD. Low-threshold EPSPs were evoked at relatively low-intensity stimulation (<20 V, 100 msec). High-threshold EPSPs were evoked at relatively high-intensity stimulation (40–80 V, 100 msec). p values were calculated using the Student's t test; *p < 0.05; **p < 0.01; ***p < 0.001; in comparison of monosynaptic EPSPs in axotomy versus high-threshold monosynaptic EPSPs in control.