Table 3. Distribution of LOXL1 polymorphisms in the Hong Kong cohort.
| SNP ID |
Allele Frequency (%) |
p value |
Genotype Frequency (%) |
p value | ||||
|---|---|---|---|---|---|---|---|---|
| Allele | Cases (n=586) | Controls (n=500) | Genotype | Cases (n=293) | Controls (n=250) | |||
|
rs1048661
(R141L) |
T |
340 (58.0) |
264 (52.8) |
0.084 |
TT |
109 (37.2) |
69 (27.6) |
0.047 |
| |
G |
246 (42.0) |
236 (47.2) |
|
GT |
122 (41.6) |
126 (50.4) |
|
| |
|
|
|
|
GG |
62 (21.2) |
55 (22.0) |
|
|
rs3825942
(G153D) |
G |
524 (89.4) |
438 (87.6) |
0.35 |
GG |
237 (80.9) |
193 (77.2) |
0.54 |
| |
A |
62 (10.6) |
62 (12.4) |
|
GA |
50 (17.1) |
52 (20.8) |
|
| |
|
|
|
|
AA |
6 (2.0) |
5 (2.0) |
|
|
rs2165241 |
C |
537 (91.6) |
449 (89.8) |
0.3 |
CC |
246 (84.0) |
199 (79.6) |
0.14 |
| |
T |
49 (8.4) |
51 (10.2) |
|
CT |
45 (15.4) |
51 (20.4) |
|
| TT | 2 (0.7) | 0 (0.0) | ||||||