Skip to main content
. 2008 Dec 19;14:2381–2389.

Table 7. Summary of the reported allele frequencies of the LOXL1 polymorphisms in POAG.

Population
  Phenotype
  Allele Frequency
Sample Size Reference
rs1048661 G rs3825942 G rs2165241 T
Iceland
Control
0.651
0.847
0.473
14474
[21]
 
POAG
0.711
0.872
0.55
90

Sweden
Control
0.682
0.879
0.535
198
[21]
 
POAG
0.638
0.863
0.488
200

U.S Caucasian
Control
0.719
0.795
0.456
88
[23]
 
POAG
0.724
0.771
0.412
331

African American
Control
NA
0.599
0.204
97
[33]
 
POAG
NA
0.617
0.237
193

India
Control
0.695
0.75
0.32
105
[34]
 
POAG
0.616
0.83
0.325
112

Japan
Control
0.493
0.877
0.058
138
[30]
 
POAG
0.395
0.911
0.048
60

Southern China
Control
0.472
0.876
0.102
250
Present study
 
POAG
0.42
0.894
0.084
293

Northern China
Control
0.497
0.865
0.084
197
Present study
  POAG 0.479 0.899 0.086 169

Allele frequencies of rs1048661 G, rs3825942 G, and rs2165241 T in POAG cases and controls among different populations were displayed in the table. In the referred studies [21,23,30,33,34] and in our present study, the SNPs were not significantly associated with POAG individually. NA: not available.