Table 1.
Alive | Dead | P | |
N | 11 | 17 | |
Age, years | 58 ± 11 | 58 ± 10 | 0.99 |
Male | 5 | 9 | 0.57 |
Type of amyloidosis | |||
AL | 10 | 14 | |
TTR | 1 | 3 | 0.67 |
NT pro-BNP (pMol/L) [N < 20] | 462 (181, 746) | 591 (456, 1176) | 0.11 |
FLC | |||
No response | 1 | 10 | |
Partial response | 5 | 4 | |
Complete response | 4 | 0 | 0.004 |
Systolic BP, mmHg | 120 ± 10 | 113 ± 5 | 0.29 |
Diastolic BP, mmHg | 70 ± 3 | 65 ± 4 | 0.10 |
Heart rate, beats/min | 75 ± 13 | 89 ± 12 | 0.02 |
NYHA functional class | |||
I | 6 | 8 | |
II | 4 | 7 | |
III | 0 | 2 | |
IV | 1 | 0 | 0.67 |
Diastolic function pattern | |||
Normal | 3 | 0 | |
Slow relaxation | 5 | 7 | |
Pseudonormal | 1 | 2 | |
Restrictive | 2 | 8 | 0.04 |
CMR dimensions and function | |||
LV EDV, mL | 108 ± 30 | 95 ± 23 | 0.20 |
LV ESV, mL | 39 ± 15 | 41 ± 21 | 0.73 |
LV SV, mL | 70 ± 21 | 54 ± 13 | 0.02 |
LV EF, % | 63 ± 10 | 58 ± 12 | 0.19 |
LV mass, g | 204 ± 79 | 201 ± 54 | 0.93 |
RV EDV, mL | 111 ± 36 | 95 ± 24 | 0.18 |
RV ESV, mL | 43 ± 20 | 42 ± 21 | 0.88 |
RV SV, mL | 68 ± 20 | 54 ± 15 | 0.045 |
RVEF, % | 61 ± 8 | 58 ± 14 | 0.43 |
RV mass, g | 72 ± 21 | 68 ± 20 | 0.64 |
AV plane descent, mm | |||
LV septum | 8 ± 3 | 6 ± 5 | 0.36 |
LV lateral wall | 9 ± 4 | 7 ± 4 | 0.28 |
RV septum | 9 ± 4 | 9 ± 3 | 0.60 |
RV lateral wall | 15 ± 7 | 12 ± 5 | 0.25 |