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Numbers of animals with orthotopic E3LZ10.7 xenografts in which metastases to distant organ sites were found
| Group |
Control, n (%) |
IPI-269609, n (%) |
|---|---|---|
| No. animals | 5 | 5 |
| Lymph nodes | 2 of 5 (40) | 0 of 5 (0) |
| Spleen | 4 of 5 (80) | 0 of 5 (0) |
| Liver | 2 of 5 (40) | 0 of 5 (0) |
| Intestine | 0 of 5 (0) | 0 of 5 (0) |
| Lungs | 0 of 5 (0) | 0 of 5 (0) |
| Peritoneum | 2 of 5 (40) | 0 of 5 (0) |
| Kidneys | 2 of 5 (40) | 0 of 5 (0) |
