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. 2008 Jun 18;28(25):6516–6525. doi: 10.1523/JNEUROSCI.0390-08.2008

Figure 4.

Figure 4.

The κ-OR antagonist nor-BNI blocks the actions of U50488 in LC, but does not alter evoked or tonic discharge. A, Representative PSTHs generated from trials of sciatic nerve stimulation before (Pre-norBNI) and immediately after (Post-norBNI) microinfusion of nor-BNI (100 ng) into the LC. The abscissas indicate the time in seconds before and after stimulus, which occurred at 0.5 s. The ordinates indicate the cumulative number of discharges (spikes) in each 8 ms bin. B, Representative PSTHs generated from trials of sciatic nerve stimulation before (Pre-U50488) and immediately after (Post-U50488) LC microinfusion of U50488 (100 ng) after local pretreatment with nor-BNI.