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. Author manuscript; available in PMC: 2008 Dec 19.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2008 Jun 5;28(8):1454–1461. doi: 10.1161/ATVBAHA.107.159392

Figure 2.

Figure 2

Treatment with VPC44116, an S1P1 antagonist, attenuates neointimal hyperplasia after acute balloon injury of the rat carotid artery. Representative cross sectional histological images of carotid artery 14 days after balloon injury in vehicle-treated (A, veh), VPC44116-treated (B, S1P1/S1P3 antagonist), and VPC01091 (S1P1 agonist/S1P3 antagonist). C, Quantitative analysis of neointimal hyperplasia plotted as the ratio neointima (NI) area to medial (M) area. n=6 for all treatment groups. Arrow heads point to the IEL.