Figure 7. PI3K inhibitor attenuates apoptosis.
Following infection with Ad-SV or Ad-MMP-9, IOMM-Lee cells were treated with 20 μM of PI3K inhibitor. Equal quantities of protein as cell lysates were subjected to immunoblotting with antibodies specific for c-JUN, pc-JUN (ser 73), pc-JUN (ser 273), Fas and PARP. GAPDH was used as a loading control. Each blot is a representative of three independent experiments.