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. Author manuscript; available in PMC: 2009 May 15.
Published in final edited form as: Neuroscience. 2008 Mar 18;153(3):733–750. doi: 10.1016/j.neuroscience.2008.02.074

Figure 6.

Figure 6

Varicosities along the vagal efferent axons innervating the myenteric ganglia were positive for alpha-synuclein, and in close proximity to myenteric neurons that were also positive for alpha-synuclein. Vagal efferent innervation (red) of the myenteric plexus was selectively labeled by injecting the tracer Dextran-Texas Red into the dorsal motor nucleus of the vagus (dmnX). Varicosities occurring on Texas Red labeled efferent axons terminating within myenteric ganglia are thought to be synaptic vesicles and thus sites of transmitter release. Myenteric neurons positive for alpha-synuclein (green) were typically encircled by alpha-synuclein-positive varicosities (A–C). In the merged images, varicosities along the vagal efferents are positive for alpha-synuclein (yellow). Scale bar in C = 25 µm for A–C.