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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Eur J Cardiothorac Surg. 2008 Feb;33(2):215–221. doi: 10.1016/j.ejcts.2007.11.008

Figure 3. Differences in thrombosis markers in the aprotinin and control groups.

Figure 3

Thrombin production and the contact activation pathway were monitored after OPCAB by measuring the trancardiac gradients of F1.2 and FXII-a. Platelet activation within the coronary circulation was assessed by determining the proportion of CD41+, Annexin+ microparticles released from the heart, normalized against the number of platelets in the sample. The aprotinin group showed significantly reduced thrombin formation (F1.2), inhibition of contact activation (FXII-a) and reduced microparticle formation within the heart after OPCAB.