Table 2.
Mean (SE) of standardized ROI volumes according to age group. Significant volume changes between young and old age (*), between middle-age and old age (#) and between young and middle-age (+) are indicated with the ROI name.
| Regions of Interest (ROI) |
|||||
|---|---|---|---|---|---|
| Age Category | Total Forebrain*# | Forebrain Parenchyma*# | Forebrain White Matter*# | Forebrain Gray Matter# | Cerebral Cortex |
| Young | 80.61 (0.64) | 78.54 (0.68) | 26.25 (0.67) | 52.28 (0.53) | 41.66 (0.61) |
| Middle-Aged | 83.06 (0.57) | 80.96 (0.59) | 27.98 (0.56) | 52.98 (0.56) | 42.36 (0.44) |
| Old | 76.57 (0.81) | 74.42 (0.80) | 23.23 (0.68) | 51.19 (0.21) | 41.58 (0.25) |
| Caudate Nucleus+# | Putamen | Globus Pallidus# | Claustrum | ||
| Young | 2.29 (0.13) | 2.65 (0.14) | 1.15 (0.09) | 0.54 (0.01) | |
| Middle-Aged | 2.81 (0.08) | 2.41 (0.16) | 1.29 (0.04) | 0.50 (0.03) | |
| Old | 2.02 (0.11) | 2.34 (0.12) | 0.94 (0.07) | 0.57 (0.02) | |
| Thalamus | Hypothalamus | Brainstem | Cerebellum | ||
| Young | 3.81 (0.29) | 0.18 (0.03) | 3.40 (0.16) | 9.56 (0.41) | |
| Middle-Aged | 3.43 (0.21) | 0.18 (0.02) | 3.26 (0.31) | 9.65 (0.55) | |
| Old | 3.52 (0.15) | 0.23 (0.02) | 3.27 (0.09) | 8.74 (0.43) | |
| Ventricular CSF | Lateral Ventricles | Third Ventricle | Cerebral Aqueduct | Fourth Ventricle | |
| Young | 2.08 (0.08) | 1.73 (0.07) | 0.12 (0.02) | 0.06 (0.00) | 0.16 (0.01) |
| Middle-Aged | 2.10 (0.06) | 1.80 (0.06) | 0.08 (0.01) | 0.06 (0.02) | 0.15 (0.02) |
| Old | 2.15 (0.06) | 1.79 (0.07) | 0.17 (0.02) | 0.06 (0.01) | 0.14 (0.01) |