Table 4.
Adjusted Odds Ratios for Developing an Internalizing, Externalizing or Any Diagnosis in Adolescence for Offspring Evaluated Between the Ages of 12 and 18 (N=338).
| Absence of Internalizing Diagnosis | Presence of Internalizing Diagnosis | Odds Ratio* | 95% CFI | q-value | Absence of Externalizing Diagnosis | Presence of Externalizing Diagnosis | Odds Ratio* | 95% CFI | q-value | Absence of Any Diagnosis | Presence of Any Diagnosis | Odds Ratio* | 95% CFI | q-value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low Risk | 130 | 26 | 132 | 24 | 112 | 44 | |||||||||
| (N = 156) | 83.3% | 16.7% | 84.6% | 15.4% | 71.8% | 28.2% | |||||||||
| High Risk | 130 | 52 | 1.91 | 1.11–3.29 | 0.043 | 102 | 80 | 4.85 | 2.80–8.40 | <0.001 | 77 | 105 | 3.64 | 2.27–5.85 | <0.001 |
| (N = 182) | 71.4% | 28.6% | 56.0% | 44.0% | 42.3% | 57.7% | |||||||||
| Neither Parent Alcoholic | 84 | 12 | 80 | 16 | 71 | 25 | |||||||||
| (N = 96) | 87.5% | 12.5% | 83.3% | 16.7% | 74.0% | 26.0% | |||||||||
| Either Parent Alcoholism | 104 | 43 | 3.14 | 1.53–6.48 | 0.005 | 82 | 65 | 4.52 | 2.36–8.68 | <0.001 | 61 | 86 | 4.74 | 2.62–8.57 | <0.001 |
| (N = 147) | 70.7% | 29.3% | 55.8% | 44.2% | 41.5% | 58.5% | |||||||||
| Mother Not Alcoholic | 161 | 40 | 155 | 46 | 128 | 73 | |||||||||
| (N = 201) | 80.1% | 19.9% | 77.1% | 22.9% | 63.7% | 36.3% | |||||||||
| Mother Alcoholic | 60 | 22 | 1.89 | 0.98–3.66 | 0.079 | 41 | 41 | 5.34 | 2.82–10.09 | <0.001 | 33 | 49 | 3.97 | 2.19–7.20 | <0.001 |
| (N = 82) | 73.2% | 26.8% | 50.0% | 50.0% | 40.2% | 59.8% | |||||||||
| Father Not Alcoholic | 112 | 20 | 110 | 22 | 96 | 36 | |||||||||
| (N = 132) | 84.8% | 15.2% | 83.3% | 16.7% | 72.7% | 27.3% | |||||||||
| Father Alcoholic | 37 | 17 | 2.24 | 0.99–5.04 | 0.079 | 34 | 20 | 2.37 | 1.11–5.09 | 0.052 | 24 | 30 | 2.63 | 1.30–5.29 | 0.017 |
| (N = 54) | 68.5% | 31.5% | 63.0% | 37.0% | 44.4% | 55.6% | |||||||||
| Neither Parent Depressed | 88 | 20 | 85 | 23 | 68 | 40 | |||||||||
| ( N = 108) | 81.5% | 18.5% | 78.7% | 21.3% | 63.0% | 37.0% | |||||||||
| Either Parent Depressed | 72 | 27 | 1.95 | 0.98–3.87 | 0.079 | 68 | 31 | 1.89 | 0.99–3.63 | 0.079 | 55 | 44 | 1.57 | 0.88–2.81 | 0.164 |
| (N = 99) | 72.7% | 27.3% | 68.7% | 31.3% | 55.6% | 44.4% | |||||||||
| Mother Not Depressed | 178 | 45 | 154 | 69 | 127 | 96 | |||||||||
| (N = 223) | 79.8% | 20.2% | 69.1% | 30.9% | 57.0% | 43.0% | |||||||||
| Mother Depressed | 46 | 21 | 1.87 | 1.00–3.48 | 0.079 | 45 | 22 | 1.07 | 0.59–1.94 | 0.814 | 34 | 33 | 1.26 | 0.72–2.19 | 0.478 |
| (N = 67) | 68.7% | 31.3% | 67.2% | 32.8% | 50.7% | 49.3% | |||||||||
| Father Not Depressed | 129 | 34 | 125 | 38 | 101 | 62 | |||||||||
| (N = 163) | 79.1% | 20.9% | 76.7% | 23.3% | 62.0% | 38.0% | |||||||||
| Father Depressed | 22 | 6 | 1.41 | 0.50–3.97 | 0.544 | 19 | 9 | 1.86 | 0.75–4.69 | 0.215 | 17 | 11 | 1.36 | 0.57–3.23 | 0.531 |
| (N = 28) | 78.6% | 21.4% | 67.9% | 32.1% | 60.7% | 39.3% | |||||||||
| Neither Parent | 106 | 23 | 102 | 27 | 87 | 42 | |||||||||
| Drug Dependence | 82.2% | 17.8% | 79.1% | 20.9% | 67.4% | 32.6% | |||||||||
| (N = 129) | |||||||||||||||
| Either Parent | 50 | 20 | 2.23 | 1.05–4.71 | 0.068 | 36 | 34 | 4.17 | 2.08–8.34 | <0.001 | 26 | 44 | 4.70 | 2.36–9.36 | <0.001 |
| Drug Dependence | 71.4% | 28.6% | 51.4% | 48.6% | 37.1% | 62.9% | |||||||||
| (N =70) | |||||||||||||||
*
Odds ratios were adjusted for the linear effects of gender, the number of repeated assessments and for sibling participation in the study.