Fig. 1.
LTP at hippocampal perforant path synapses is impaired in mice lacking the EP2. (A1) Representative traces of fEPSPs recorded at hippocampal perforant path synapses before (black) and after TBS (red) in EP2 WT and KO mice (red). (A2) Time course of the TBS-induced changes in fEPSP slopes. (A3) Mean values of the potentiation of fEPSPs averaged from 36 to 40 min following TBS at hippocampal perforant path synapses. **P< 0.01 compared with the WT control. (Numbers in the bar graphs denote the number of observations). (B1) Representative traces of fEPSPs in EP2 WT and KO mice. (B2) Input-output function curves at perforant path in EP2 WT and KO.