Skip to main content
. Author manuscript; available in PMC: 2009 Dec 19.
Published in final edited form as: Neurosci Lett. 2008 Oct 14;448(1):157–160. doi: 10.1016/j.neulet.2008.10.025

Figure 1.

Figure 1

Evoked neuronal activity is enhanced in the NAc of f/fc-fos-D1-cre (mutant) mice as compared to wild-type mice. (A) Representative traces showing that depolarizing currents evoke more action potentials in NAc neurons in f/fc-fos-D1-cre mice compared to those in wild-type mice (n=10-12 cells per group). (B) There is a significant difference in current-evoked spike response curves between NAc neurons in wild-type and f/fc-fos-D1-cre mice (F1,12=5.50; p < 0.05, Newman-Keuls test, *p < 0.05). (C) Representative action potential traces indicate that the amplitude of action potentials (AP) and after-hyperpolarization (AHP) was reduced in NAc neurons in f/fc-fos-D1-cre mice compared to wild-type mice. (D) The current-voltage relationship shows that the inward rectification during membrane hyperpolarization is not affected by the Fos mutation in f/fc-fos-D1-cre mice.