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. Author manuscript; available in PMC: 2009 Dec 19.
Published in final edited form as: Neurosci Lett. 2008 Oct 14;448(1):157–160. doi: 10.1016/j.neulet.2008.10.025

Table 1.

Comparison of membrane properties of NAc neurons in wild type and Fos mutant mice

Group Wild-Type Mutant
Number of neurons 10 12
Passive Membrane properties
RMP (mV) -79.02 ± 0.93 -79.37 ± 0.41
Rin (mW) 128.65 ± 24.59 159.17 ± 15.90
Active Membrane Properties
Current to generate AP (nA) 0.29 ± 0.04 0.20 ± 0.01 *
AP threshold (mV) -33.93 ± 1.09 -34.27 ± 1.19
AP amplitude (mV) 74.86 ± 1.86 67.83 ± 1.67 *
½AP duration (msec) 1.09 ± 0.05 1.17 ± 0.04
AHP amplitude (mV) 13.51 ± 1.05 9.83 ± 0.67 *

The passive and active membrane properties of medium spiny NAc neurons were measured by current clamp recordings from brain slices of wild-type and f/fc-fos-D1-cre mice. Values represent the mean±SEM for the number of neurons indicated (*p < 0.05; Student's t-test).

RMP: resting membrane potential; AP: action potential; AHP: after-hyperpolarization.