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. Author manuscript; available in PMC: 2009 Oct 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Jul 4;232(2):169–179. doi: 10.1016/j.taap.2008.06.017

Fig. 10.

Fig. 10

Caspase activation in ATG7 knockdown cultures. Nonsense-C shRNA (A) and ATG7-H shRNA (B) cultures were treated with either nothing (X), DMSO (○), 50 μM (◆) or 100 μM (●) pAA for different lengths of time before being harvested for DEVDase analyses. Data represents means ± SD for three determinations made on a single sample. (C) Western blot analysis of pro-caspase-3 activation in Nonsense C and ATG7-H cultures following exposure to 100 μM pAA. Each lane contained 40 μg of protein. Similar results were obtained in a second experiment.