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E6-AP interacts with PPARα. 293T cells were transfected with plasmids expressing pFR-Luciferase, pRLCMV, pVP16-PPARα, pM-E6-AP. Cells were lysed and luciferase activity was corrected for transfection efficiency and protein. Asterisks indicate a significant difference in Wy-14,643 induction when compared to the corresponding DMSO group. (*P < .05 with statistical analysis using ANOVA). The graph is representative of 2 independent experiments.
