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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: J Neurochem. 2009 Jan;108(1):190–201. doi: 10.1111/j.1471-4159.2008.05751.x

Figure 4. Wortmannin does not alter the properties of GABAA receptors.

Figure 4

A,B, Plot of the pooled data illustrating the effects of pentobarbitone on eIPSC amplitude in control (A) and wortmannin treated (B) slices. Below the plot are representative synaptic current traces obtained in control conditions (A1) or in the presence of wortmannin (B1), and following addition of pentobarbitone (A2) or in the combined presence of wortmannin and pentobarbitone (B2). In (A3 and B3) the superimposed synaptic currents obtained in (1) and (2) illustrate that pentobarbitone significantly alters the decay kinetics of eIPSCs. B, Histogram of the pooled data of normalised eIPSC amplitude in control conditions, following application of pentobarbitone and in the combined presence of wortmannin and pentobarbitone.