NAD(P)H and ΔΨm during APD
oscillations. A, simultaneous recordings of NAD(P)H
autofluorescence (FNAD(P)H; red) and APD
(black) from a myocyte exposed to glucose-free buffer containing 450
μm 3-merc plus 5 mm cyanide. A1, expanded
traces between 350–450 s, showing that APD and
FNAD(P)H are oscillating out of phase. B and
B1, corresponding simulations from the detailed model (see
supplemental material). a.u., arbitrary units.