FIGURE 2.
Eag1-G440S-expressing cells form tumors. A, tumor weight comparisons between xenografted Eag1-wt (n = 9), Eag1-G440S (n = 10), Eag2-wt (n = 10), or vector-transfected (n = 10) NIH3T3 cells. Eag1-G440S-expressing cells statistically equivalent tumors as Eag1-transfected cells (p = 0.3). B, CHO cells transfected with Eag1-(n = 16), Eag1-G440S (n = 16), Eag2-(n = 15), or vector (n = 5) show similar behavior, albeit G440S-expressing tumors are significantly smaller. n.s., nonsignificant; ***, p < 0.001.