Table 1.
Parameter | MGUS (n = 32) | PCM (n = 32) | P value | Reference range |
Age | 59 ± 12 | 62 ± 12 | 0.17 | - |
M:F | 1:1 | 1.9:1 | - | - |
Hemoglobin, g/L | 121 ± 16 | 99 ± 21 | <0.005 | 121 – 161 |
Total protein, g/L | 75 ± 13 | 73 ± 19 | 0.29 | 63 – 82 |
M component, g/L | 10 ± 9 | 38 ± 20 | <0.005 | - |
Calcium, g/L | 0.089 ± 0.009 | 0.09 ± 0.011 | 0.28 | 0.084–0.102 |
β2-microglobulin, mg/L | 2.4 ± 1.3 | 4.9 ± 3.6 | 0.02 | 0.7–1.8 |
Lactate dehydrogenase, U/L | 184 ± 50 | 271 ± 99 | <0.005 | 100 – 190 |
Osteolytic bone lesions | 0% | 100% | <0.005 | - |
Number of reduced Ig classes | 0.2 ± 0.6 | 1.9 ± 0.4 | <0.005 | - |
% plasma cells by morphology | 4.2 ± 2.3 | 41 ± 21 | <0.005 | - |
% plasma cells by flow cytometry | 0.7 ± 0.8 | 19 ± 16 | <0.005 | - |