Table 1.
Compound | Adjuvant factora (dose of test compound) | |
1 booster | 2 boosters | |
1: Di-n-butyl phthalate | NDb | 24 (10 μg)c |
2: Benzyl butyl phthalate | 1d | 1d |
3: Di-(2-ethylhexyl) phthalate (DEHP) | 13 (10 μg) | |
33 (100 μg) | 61 (100 μg) | |
4: Butyldodecyl phthalate (BDP) | 20 (10 μg) | |
14 (100 μg) | 68 (100 μg) | |
5: Di-n-octyl phthalate | ND | 61 (100 μg)c |
6: Bis-(2-ethylhexyl) terephthalate (DOTP) | 1 | 4 (100 μg) |
7: Diisononyl phthalate | ND | 42 (both 10 and 100 μg)c |
8: Diisodecyl phthalate | ND | 1c |
9: Trioctyl trimellitate (TOTM) | 1 | 1 |
10: Methylpalmitate (MP) | 1 | 1 |
a) Adjuvant factor taken as the ratio between the IgG1 level in the test group and the OVA control group.
b) ND: Not defined, as the median IgG1 value in the OVA control group was zero.
c) Data are calculated from reference 5. Cf. 'Material and Method' for details.
d) Data are calculated from reference 11. Cf. 'Material and Method' for details.