Table 1.
Baseline characteristics according to the presence of metabolic syndrome and associations between the different components of the metabolic syndrome: the 3C Study, France, 1999–2004
| Total cohort | Metabolic syndrome | No metabolic syndrome | P | Components of the metabolic syndrome |
|||||
|---|---|---|---|---|---|---|---|---|---|
| High blood pressure | High waist circumference | High triglycerides | Low HDL cholesterol | High glycemia | |||||
| n | 7,087 | 1,121 | 5,966 | 6,064 | 2,049 | 1,247 | 741 | 816 | |
| Age (years) | 73.4 ± 4.9 | 73.8 ± 4.8 | 73.4 ± 4.9 | 0.05 | 73.7 ± 4.9 | 74.0 ± 4.9 | 73.3 ± 4.9 | 73.6 ± 4.9 | 73.2 ± 4.7 |
| Men (%) | 39.0 | 41.6 | 38.5 | 0.05 | 40.8 | 32.3 | 45.9 | 35.4 | 39.0 |
| Education level (no or primary) | 23.6 | 29.1 | 22.6 | <0.0001 | 24.4 | 28.8 | 25.9 | 29.9 | 23.6 |
| ApoE ε4* | 20.4 | 21.0 | 20.3 | 0.60 | 20.3 | 19.6 | 20.4 | 23.5 | 20.4 |
| High blood pressure† | 85.6 | 98.2 | 83.2 | <0.0001 | NA | 91.6 | 90.0 | 88.3 | 95.2 |
| High waist circumference‡ | 28.9 | 78.5 | 19.6 | <0.0001 | 31.0 | NA | 44.2 | 50.4 | 50.2 |
| High triglycerides§ | 17.6 | 66.4 | 8.4 | <0.0001 | 18.5 | 26.9 | NA | 50.5 | 32.0 |
| Low HDL cholesterol‖ | 10.5 | 47.6 | 3.5 | <0.0001 | 10.8 | 18.3 | 30.2 | NA | 22.8 |
| High glycemia¶ | 11.5 | 47.6 | 4.7 | <0.0001 | 12.9 | 20.0 | 20.9 | 25.0 | NA |
| Impaired fasting glucose without diabetes** | 3.9 | 15.3 | 1.8 | <0.0001 | 4.3 | 6.9 | 6.1 | 7.0 | 34.2 |
| Diabetes†† | 7.6 | 32.3 | 2.9 | <0.0001 | 8.6 | 13.1 | 14.8 | 18.0 | 65.8 |
Data are means ± SD or percent. Metabolic syndrome was defined by the NCEP ATP III criteria.
ApoE ε4: presence of at least one allele ε4 in apoE genotype.
Systolic blood pressure >130 mmHg or diastolic blood pressure >85 mmHg or medication.
Waist circumference >88 cm in women or >102 cm in men.
Triglycerides ≥150 mg/dl.
HDL cholesterol <50 mg/dl in women or <40 mg/dl in men.
Fasting glycemia ≥110 mg/dl or nonfasting glycemia ≥200 mg/dl or antidiabetes medication.
Impaired fasting glucose ≥110 mg/dl without diabetes.
Diabetes: fasting glycemia ≥126 mg/dl or nonfasting glycemia ≥200 mg/dl or antidiabetes medication. P value: Student and Pearson χ2 tests used for continuous and categorical variables, respectively, to compare baseline characteristics between subjects with metabolic syndrome and those without. NA, nonapplicable.