Table 1.
Treatment groups | 1995 (n = 1,470) |
2005 (n = 2,699) |
Differences between 1995 and 2005 | P* | ||||
---|---|---|---|---|---|---|---|---|
Total patients | Patients measured | Performance | Total patients | Patients measured | Performance | |||
A1C (%) | ||||||||
Diet alone | 30.7 (452) | 84.7 (383) | 6.75 ± 0.98 | 28.4 (766) | 86.3 (661) | 6.46 ± 0.85 | 0.29 (0.18–0.41) | <0.001 |
Metformin alone | 2.2 (33) | 87.5 (28) | 7.78 ± 1.42 | 17.3 (467) | 94.9 (443) | 6.93 ± 0.99 | 0.85 (0.46–1.24) | <0.001 |
Sulfonylurea alone | 33.5 (491) | 88.8 (436) | 7.74 ± 1.43 | 12.9 (348) | 93.7 (326) | 7.16 ± 1.14 | 0.58 (0.39–0.77) | <0.001 |
Metformin and sulfonylurea | 5.4 (80) | 95.0 (76) | 8.52 ± 1.86 | 13.9 (374) | 96.5 (361) | 7.38 ± 1.06 | 1.31 (0.82–1.44) | <0.001 |
Insulin alone | 25.4 (374) | 90.1 (337) | 8.52 ± 1.65 | 15.6 (422) | 93.8 (396) | 7.79 ± 1.26 | 0.73 (0.51–0.94) | <0.001 |
Insulin and oral agents | 1.1 (17) | 100 (17) | 8.66 ± 1.61 | 9.4 (255) | 95.3 (243) | 7.78 ± 1.30 | 0.88 (0.20–1.56) | 0.011 |
Overall | 88.5 (1,301) | 7.74 ± 1.59 | 92.5 (2,496) | 7.15 ± 1.20 | 0.59 (0.50–0.68) | <0.001 | ||
SBP (mmHg) | ||||||||
Not on BP-lowering therapy | 52.2 (767) | 82.1 (630) | 146.2 ± 20.9 | 34.9 (942) | 82.5 (777) | 134.9 ± 17.4 | 11.2 (9.2–13.3) | <0.001 |
BP-lowering therapy | 47.8 (703) | 91.3 (642) | 153.8 ± 22.3 | 65.1 (1,757) | 94.1 (1,653) | 143.0 ± 19.5 | 10.8 (8.9–12.6) | <0.001 |
Overall | 86.5 (1,272) | 150.0 ± 22.0 | 90.0 (2,430) | 140.4 ± 19.2 | 9.6 (8.2–10.9) | <0.001 | ||
Cholesterol (mmol/l) | ||||||||
Not on statin therapy | 95.2 (1,399) | 46.6 (652) | 6.31 ± 1.37 | 54.3 (1,465) | 80.8 (1,184) | 5.43 ± 1.08 | 0.89 (0.77–1.00) | <0.001 |
Statin therapy | 4.8 (71) | 95.8 (68) | 5.99 ± 1.54 | 45.7 (1,234) | 96.1 (1,186) | 4.63 ± 1.0 | 1.36 (1.11–1.62) | <0.001 |
Overall | 50 (720) | 6.28 ± 1.39 | 87.8 (2,370) | 5.0 ± 1.1 | 1.26 (1.16–1.35) | <0.001 | ||
Achievement of national targets (%) | ||||||||
A1C ≤7.5% | 51.3 | 69.2 | 17.9 (12.5–23.3) | <0.001 | ||||
SBP ≤140 mmHg | 46.7 | 65.7 | 19.0 (14.5–23.5) | <0.001 | ||||
DBP ≤85 mmHg | 64.5 | 78.1 | 13.6 (8.6–18.7) | <0.001 | ||||
Cholesterol ≤5 mmol/l | 16.8 | 52.9 | 36.2 (30.7–41.6) | <0.001 | ||||
All four targets | 4.2 | 22.7 | 18.5 (15.2–21.7) | <0.001 |
Data are % (n), means ± SD, or differences (95% CI) unless otherwise indicated.
P values for differences in means of outcome measures are derived from an age- and sex-adjusted ANOVA analysis. P values for differences in percentage achieving national targets are adjusted for clustering by using practice-specific means as proportions in a paired t test. BP, blood pressure; DBP, diastolic blood pressure; SBP, systolic blood pressure.