Table 2.
Prevalence of metabolic syndrome defined by WHO and ATP-III criteria and components by CAC score category at baseline
| CAC score category |
P | ||||
|---|---|---|---|---|---|
| None/minimal | Mild | Moderate | Severe | ||
| n | 125 | 73 | 66 | 74 | |
| Prevalence of WHO components (%) | |||||
| Impaired glucose metabolism (type 2 diabetes, impaired fasting glucose [110–125 mg/dl] or impaired glucose tolerance [140–199 mg/dl]) | 7.2 | 17.8 | 28.8 | 31.1 | <0.001 |
| Obesity (BMI >30 kg/m2 and/or waist-to-hip ratio >0.9 for men and >0.85 for women) | 40.0 | 68.5 | 71.2 | 82.4 | <0.001 |
| High triglycerides (≥150 mg/dl) | 28.0 | 28.8 | 30.3 | 31.1 | 0.61 |
| Low HDL cholesterol (<35 mg/dl for men and <39 mg/dl for women) | 0.8 | 2.7 | 6.1 | 4.1 | 0.08 |
| Hypertension (≥140/90 mmHg or use of antihypertensive drugs) | 32.8 | 44.3 | 53 | 55.4 | 0.001 |
| Albuminuria (urinary albumin excretion rate ≥20 μg/min or albumin-to-creatinine ratio ≥30 mg/g)* | 4.5 | 1.6 | 3.6 | 4.8 | 0.90 |
| Prevalence of ATP-III components (%) | |||||
| Fasting plasma glucose >110 mg/dl | 7.2 | 17.8 | 27.3 | 31.1 | <0.001 |
| Abdominal obesity (waist circumference >102 cm for men and >88 cm for women) | 17.6 | 20.5 | 19.7 | 28.4 | 0.10 |
| High triglycerides (≥150 mg/dl) | 28.0 | 28.8 | 30.3 | 31.1 | 0.61 |
| Low HDL cholesterol (<40 mg/dl for men and <50 mg/dl for women) | 15.2 | 17.8 | 18.2 | 13.1 | 0.87 |
| Hypertension (≥130/85 mmHg or use of antihypertensive drugs) | 40.8 | 61.6 | 66.7 | 67.6 | <0.001 |
*
N = 292: none/minimal CAC, n = 112; mild CAC, n = 63; moderate CAC, n = 55; and severe CAC, n = 62.