Table 4.
Characteristics according to A-FABP tertile levels
| A-FABP tertile |
P | |||
|---|---|---|---|---|
| 1 (<8.6 μg/l [men], <150 μg/l [women]) | 2 (8.6–14.3 μg/l [men], 15.0–24.1 μg/l [women]) | 3 (>14.3 μg/l [men], >24.1 μg/l [women]) | ||
| Age (years) | 53.1 ± 8.1 | 55.3 ± 11.4 | 54.4 ± 11.4 | 0.5 |
| BMI (kg/m2) | 24.6 ± 3.2 | 25.8 ± 3.1 | 26.3 ± 3.5† | 0.02 |
| Waist circumference (cm) | 85.0 ± 7.0 | 89.3 ± 7.7† | 91.6 ± 9.2‡ | <0.001 |
| WHR | 0.91 ± 0.05 | 0.93 ± 0.05* | 0.95 ± 0.06‡ | 0.001 |
| Triglycerides (mg/dl) | 148.9 ± 94.1 | 190.1 ± 124.3* | 187.3 ± 82.1* | 0.05 |
| HDL cholesterol (mg/dl) | 52.6 ± 11.6 | 45.7 ± 9.3† | 46.7 ± 11.9† | 0.001 |
| A-FABP (μg/l) | 9.0 ± 2.9 | 14.6 ± 4.2† | 31.1 ± 16.9‡ | <0.001 |
| RBP-4 (μg/ml) | 67.1 ± 19.6 | 78.6 ± 34.4 | 73.4 ± 31.5 | 0.1 |
| Adiponectin (μg/ml) | 4.3 ± 2.0 | 3.9 ± 2.2 | 4.4 ± 3.0 | 0.5 |
| CRP (mg/l) | 1.70 ± 3.55 | 2.57 ± 4.14 | 3.39 ± 4.69* | 0.1 |
| FPG (mg/dl) | 172.5 ± 69.2 | 188.2 ± 119.3 | 192.5 ± 70.4 | 0.4 |
| Fasting insulin (μU/ml) | 7.7 ± 7.6 | 7.3 ± 6.2 | 10.1 ± 7.5 | 0.07 |
| HOMA-IR | 3.2 ± 3.3 | 3.3 ± 3.2 | 4.3 ± 2.8 | 0.08 |
| A1C (%) | 8.1 ± 2.0 | 8.6 ± 2.3 | 9.1 ± 2.4* | 0.04 |
| 24-h albumin (mg/day) | 29.3 ± 38.2 | 29.0 ± 26.3 | 40.4 ± 52.6 | 0.2 |
| Serum creatinine (mg/dl) | 0.76 ± 0.16 | 0.82 ± 0.24 | 0.84 ± 0.21* | 0.1 |
| Estimated GFR (ml/min/1.73 m2) | 103.8 ± 19.6 | 96.5 ± 26.7 | 94.5 ± 23.4* | 0.08 |
| Metabolic syndrome (n [%]) | 25 (43.1) | 46 (76.7)‡ | 48 (78.7)‡ | <0.001 |
Data are means ± SD unless indicated otherwise. P = the difference among three groups using ANOVA test.
*
P < 0.05 compared with tertile 1.
†
P < 0.01 compared with tertile 1.
‡
P < 0.001 compared with tertile 1. FPG, fasting plasma glucose.