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. 2009 Jan;58(1):165–173. doi: 10.2337/db08-0275

FIG. 2.

FIG. 2.

Life table analysis of islet allograft survival in chemically diabetic congenic NOD mice. The 6- to 8-week-old male mice were treated with a DST plus anti-CD154 mAb. DST (107 C3H/He spleen cells) was given on day −7, and anti-CD154 mAb (0.5 mg/dose) was given on days −7, −4, 0, and +4 relative to transplantation with C3H/He islets on day 0. Vertical bars indicate mice removed from the study with intact grafts or alive with intact grafts at the conclusion of the period of observation. Comparative P values of islet allograft survival in the groups are shown. A: Idd10 Idd18 and Idd3 Idd10 Idd18 congenic NOD mice. B: Idd3, Idd5, and Idd3/Idd5 congenic NOD mice. Islet allograft survival in C57BL/6 and NOD mice shown in A is reproduced in B for ease of comparison with other strains.