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Scatter plot of alloreactive CD8+ T-cell deletion in synchimeric mice. (KB5 CBA × C57BL/6.H2g7)F1 mice and (KB5 CBA × NOD)F1 synchimeric mice were treated with a C57BL/6 DST on day −7 and anti-CD154 mAb on days −7 and −4 relative to analysis of their circulating levels of KB5 transgenic CD8+ T-cells on day 0 as described in research design and methods. P values are indicated by horizontal bars.
