TABLE 2.
Linkage results with LOD > 1.0 and multilocus conditional logistic regression results
| Chromosome | Position (cM) | Flanking markers | Primary linkage analysis
|
Multilocus conditional logistic regression analysis
|
|||
|---|---|---|---|---|---|---|---|
| LOD | LOD-1 interval | P value | LOD | LOD-1 interval | |||
| 1 | 167.5 | rs1319898/rs869714 | 1.51 | 155.0–181.5 | 0.00842 | ||
| 3 | 121.0 | rs1317244/rs12736 | 1.61 | 113.5–127.5 | 0.0064 | ||
| 7 | 29.5 | rs726395/rs1029718 | 1.15 | 7.0–96.5 | 0.0212 | 1.62* | 23.0–55.0 |
| 7 | 44.5 | rs1404282/rs1860759 | 1.18 | 7.5–60.5 | 0.0195 | ||
| 7 | 78.0 | rs1105305/rs517258 | 1.64 | 64.5–88.5 | 0.00598 | ||
| 14 | 123.6 | rs1132975/rs988131 | 2.10 | 117.1-tel | 0.00189 | 2.52* | 118.39-tel |
*
The evidence for linkage on 7p is adjusted for linkage on 14q, and similarly, the 14q locus is adjusted for linkage at 7p.