TABLE 4.
Adjusted OR (95% CI) of dementia, Alzheimer's disease, and vascular dementia related to diabetes and separately to diabetes with onset before and after age 65 years: results from GEE models
| Subjects (n) | All dementia | Alzheimer's disease | Vascular dementia | |
|---|---|---|---|---|
| Diabetes status | ||||
| No | 12,296 | 498; 1.00 (reference); 1.00 (reference) | 236; 1.00 (reference); 1.00 (reference) | 74; 1.00 (reference); 1.00 (reference) |
| Yes | 1,396 | 139; 2.45 (1.97–3.03)*; 1.89 (1.51–2.38)† | 56; 2.03 (1.47–2.80)*; 1.69 (1.16–2.36)† | 31; 3.60 (2.33–5.57)*; 2.17 (1.36–3.47)† |
| Age of diabetes onset | ||||
| <65 years | 643 | 48; 2.95 (2.14–4.08)*; 2.76 (1.97–3.87)† | 16; 2.32 (1.37–3.94)*; 2.25 (1.29–3.92)† | 12; 4.94 (2.61–9.35)*; 3.94 (1.90–8.15)† |
| ≥65 years | 753 | 91; 2.12 (1.64–2.75)*; 1.63 (1.23–2.16)† | 40; 1.88 (1.29–2.74)*; 1.56 (1.05–2.32)† | 19; 2.90 (1.70–4.94)*; 1.62 (0.92–2.80)† |
Data are n; OR (95% CI) or OR (95% CI).
*
Adjusted for age, sex, and education.
†
Adjusted for age, sex, education, stroke, heart disease, hypertension, and BMI.