Table 4.
Odds ratios from univariate logistic regression models for parametrial invasion by modality based on the prospective reads, along with the estimated diagnostic probabilities and ROC AUC for detection of histologic lymph node involvement. Threshold was bilateral or unilateral invasion versus no invasion
| Response | Modality | Odds ratio (95% CI) | NPV | PPV | Sensitivity | Specificity | AUC (SE) |
|---|---|---|---|---|---|---|---|
| Histologic lymph node involvement specific to the common iliac nodes | MRI | 1.9 (0.7, 5.0) | 0.89 | 0.19 | 0.38 | 0.76 | 0.58 (0.06) |
| CT | 3.9 (1.4, 11.0) | 0.90 | 0.29 | 0.35 | 0.88 | 0.61 (0.06) | |
| Clinical | 3.7 (0.6, 21.8) | 0.88 | 0.33 | 0.1 | 0.97 | 0.54 (0.04) | |
| Pathologic | 7.6 (1.8, 31.5) | 0.95 | 0.29 | 0.40 | 0.92 | 0.66 (0.08) | |
| General histologic lymph node involvement (Any positive node) | MRI | 2.9 (1.4, 5.9) | 0.72 | 0.52 | 0.40 | 0.81 | 0.61 (0.04) |
| CT | 2.7 (1.1, 6.5) | 0.70 | 0.54 | 0.24 | 0.90 | 0.57 (0.03) | |
| Clinical | 4.2 (0.7, 23.7) | 0.68 | 0.67 | 0.08 | 0.98 | 0.53 (0.02) | |
| Pathologic | 9.5 (2.7, 32.8) | 0.79 | 0.71 | 0.29 | 0.96 | 0.62 (0.04) |