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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2008 Jul 7;7(9):1455–1470. doi: 10.1016/j.dnarep.2008.05.009

Fig. 11.

Fig. 11

Schematic representation of the various Rev1 C-terminal deletion fragments. The 985 amino acid Rev1 protein consists of the N-terminal BRCT region, the polymerase domain (amino acids 297–746) comprising the N-digit that interacts with the incoming dCTP and the fingers, palm, thumb and PAD domains conserved among Y-family polymerases. The Rev1 C-terminal region is composed of two copies of the Ubiquitin-Binding Motif (UBM1 and UBM2). The hatched region in the figure represents Region 1 of the Rev1 C-terminus and the bars within this region, the short peptide motifs. On the right is a summary of the regions of Rev1 that confer the dominant–negative phenotype on survival after DNA damage and that interact with Rev7. ND: Not determined.