Skip to main content
. 2009 Jan;133(1):69–77. doi: 10.1085/jgp.200810049

Figure 3.

Figure 3.

Functional characterization of the Cd2+-dependent effect in G551D-CFTR. (A) Activation of G551D-CFTR by Cd2+ is phosphorylation dependent. Note that in the same patch, Cd2+ only increases the activity of G551D-CFTR after the channels are activated by PKA and ATP. (B) A CFTR-specific blocker, inh-172, can inhibit the G551D-CFTR current induced by 200 μM Cd2+.