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. 2009 Jan;133(1):69–77. doi: 10.1085/jgp.200810049

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© 2009 Wang et al.

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Figure 5. — Comparison of Cd²⁺ and ATP-induced currents between G551A and G551C mutants. (A) Representative current trace of G551A-CFTR. Although G551A-CFTR remains ATP dependent, Cd²⁺ fails to increase the activity of the channels. (B) The ratio of currents induced by 10 μM Cd²⁺ and those with 1 mM ATP for G551C-CFTR and G551A-CFTR.