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Effect of LPS on xCT mRNA in the lung. C57BL/6 mice were treated with 1 mg/kg intraperitoneal LPS (solid circles) or with PBS (open circles). At 2, 6, 24, and 48 hours, mice were killed and lung samples were obtained. RNA was extracted from whole lung and transcript levels of xCT were quantified using quantitative RT-PCR. Data are expressed as means ± SEM. aValues significantly different from untreated controls; bvalues significantly different from corresponding pair-fed PBS control.
