Table 3.
Measures of discrimination, calibration and model fit for SHARF T0, Mehta and UK APACHE II
| SHARF T0 | SHARF II0 | Mehta | UK APACHE II | |
| Discrimination (AUC [95% CI]) | 0.632 (0.624–0.640) | 0.668 (0.660–0.676) | 0.693 (0.686–0.701) | 0.74 (0.733–0.748) |
| Calibration (mortality ratio [95% CI]) | 0.759 (0.747–0.771) | 0.950 (0.936–0.965) | 1.223 (1.205–1.242) | 1.147 (1.129–1.165) |
| Hosmer-Lemeshow (C-statistic [P value]) | 20,894 (< 0.001) | 2,575 (< 0.001) | 2,170 (< 0.001) | 575 (< 0.001) |
| Cox's regression calibration: | ||||
| Slope (95% CI) | 0.247 (0.229–0.266) | 0.415 (0.390–0.439) | 0.444 (0.417–0.470) | 0.753 (0.720–0.787) |
| Intercept (95% CI) | -0.195 (-0.243 to -0.153) | 0.005 (-0.031 to -0.040) | 0.314 (0.278–0.350) | 0.306 (0.269–0.343) |
| χ2 (1) (P value)a | 11,598 (< 0.001) | 2,303 (< 0.001) | 2,602 (< 0.001) | 596 (< 0.001) |
| Fit (Shapiro's Q [R statistic]) | 0.392 | 0.491 | 0.487 | 0.539 |
aChi-squared statistic on one degree of freedom (and associated P value) from a likelihood ratio test of slope = 1, intercept = 0 in Cox's regression calibration model. APACHE, Acute Physiology and Chronic Health Evaluation; AUC, area under the receiver operating characteristic curve; CI, confidence interval; SHARF, Stuivenberg Hospital Acute Renal Failure.