Relationship between pulse pressure and probability for stroke in a series of 703 patients after cardiac surgery. There was a significant relationship between rising pulse pressure and risk for perioperative stroke. In a Cox model, pulse pressure was an independent predictor of stroke (hazard ratio, 1.32, 95% confidence interval, 1.12 to 1.57 for every 10 mmHg increase in pulse pressure, p = 0.001). (Reprinted with permission from Benjo A, Thompson RE, Fine D, et al. Hypertension 2007;50:630–5.)