TABLE 1.
List of genes up or down regulated in the treatment groups
| Description (Mus musculus mRNA) | Fold change | |||
|---|---|---|---|---|
| 1 | 2 | 3 | 4 | |
| Cytochrome P-450, family 1, subfamily a, polypeptide 1 (Cyp1a1) | 11.7 | 1.3 | 8.2 | −1.0 |
| Cysteine-rich protein 61 (Cyr61) | −1.9 | −1.3 | −1.1 | −1.4 |
| RIKEN cDNA 1300002F13 gene (1300002F13Rik) | −1.8 | −1.4 | −1.0 | −1.3 |
| H2A histone family, member Y (H2afy) | 1.8 | −1.2 | 1.1 | 1.0 |
| Serine (or cysteine) proteinase inhibitor, clade E, member 1 (Serpine1) | −1.7 | −1.5 | −1.3 | −1.5 |
| DNA segment, Chr 4, expressed (D4Wsu53e) | 1.6 | 1.1 | 1.2 | 1.1 |
| Basic helix–loop–helix domain containing, class B2 (Bhlhb2) | −1.5 | −1.2 | −1.1 | −1.2 |
| Karyopherin (importin) alpha 2 (Kpna2) | 1.5 | 1.1 | 1.0 | 1.0 |
| Small proline-rich protein 1A (Sprr1a) | −1.5 | 1.2 | −1.0 | −1.2 |
| Lipin 3 (Lpin3) | −1.4 | 1.2 | −1.0 | −1.1 |
| Colony-stimulating factor 1 (macrophage) (Csf1) | −1.4 | 1.0 | −1.1 | −1.0 |
| Unknown | −1.3 | 1.1 | 1.0 | −1.1 |
| A kinase (PRKA) anchor protein (gravin) 12 (Akap12) | −1.3 | 1.0 | −1.0 | −1.1 |
| Carbamoyl-phosphate synthetase 1 | −1.1 | −1.3 | 1.3 | 1.3 |
| RIKEN cDNA 4632404H22 gene (4632404H22Rik) | −1.2 | −1.2 | 1.3 | −1.1 |
Note. Fold induction over matched controls for treatment groups: 1, 6 wk smoke; 2, 6 wk smoke followed by 6 wk break; 3, 12 wk smoke; 4, 12 wk smoke followed by 6 wk break. Negative values indicate downregulated genes.