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. Author manuscript; available in PMC: 2009 Mar 5.
Published in final edited form as: Mol Cell. 2008 Sep 5;31(5):737–748. doi: 10.1016/j.molcel.2008.08.011

Figure 2. Structure of unliganded LIF-R and comparison with the LIF-R/LIF complex.

Figure 2

(A) Surface representations of unliganded human LIF-R D1-D5. Sugar residues modeled into the structure are colored yellow. (B) Overlay of human LIF-R onto mouse LIF-R/LIF structure. The D3 Ig domain of human LIF-R (purple) was aligned with the D3 Ig domain of mouse LIF-R (blue), with the cytokine LIF shown in gold. Receptor interaction sites 1, 2, and 3 on LIF-R are circled.