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. 2008 Sep 22;155(8):1224–1234. doi: 10.1038/bjp.2008.360

Figure 4.

Figure 4

Contractile responses to noradrenaline in mouse vas deferens (epididymal portion). (a) Effects of prazosin and silodosin on the contractile responses to 10 μM noradrenaline (NA) in the vas deferens isolated from WT mice. In contrast to silodosin (3 nM), prazosin (10 nM) failed to inhibit the contractile response to noradrenaline. (b) Effects of prazosin, silodosin, 5-methylurapidil (5-MU) and BMY 7378 on the concentration–response curves for noradrenaline in the WT mouse vas deferens. Mean±s.e.mean of 4–6 experiments. WT, wild type.