Skip to main content
. 2008 Aug 25;155(8):1297–1306. doi: 10.1038/bjp.2008.335

Figure 2.

Figure 2

Carrageenan-evoked changes in receptive field size of wide dynamic range (WDR) neurons to 8 (a) and 26 g (b) stimulation following intraplantar administration of vehicle, WY14643 ([[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]acetic acid; 100 μg in 50 μL) or URB597 (3′-carbamoyl-biphenyl-3-yl-cyclohexylcarbamate; 25 μg in 50 μL) alone or in the presence of AM251 (N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide; 30 μg in 50 μL) or GW6471 (30 μg in 50 μL). Statistical analyses comparing area under the curve (AUC) values were performed using the Mann–Whitney test. *P<0.05, compared with vehicle. +P<0.05, **P<0.01 compared with URB597 alone. Data are expressed as mean AUC±s.e.mean.